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Ergonine by PES

Ergonine by PES

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Product Description

Ergonine by PES

ERGONINE…9 ingredients with proven or potential ergogenic/myogenic aids. And we’ve taken these 9 ingredients and supercharged them, and combined them to create a truly supreme product at an unbelievable value. How do we do it? AthletixSports.com/TheDifference tells the story.

You’ve probably heard the term “staple supplement.” This essentially means your “bread and butter” supplements, the ones that have stood the test of time and have been shown in countless studies to yield a positive effect. You take your staple supplements on a daily basis in an effort to continue reaching your goals and breaking personal records. They never leave…they travel with you on vacation and you nearly have a breakdown when you forget to take them. ERGONINE is your premium formulated staple.

There aren’t just one or two staple supplements. There’s a whole handful…and then there’s some new kids on the block that you may not know you need to be taking every day. You see with so many different, often nasty-tasting powders to scarf down on a daily basis, people miss servings, lack consistency, and ultimately fail to benefit from these time-tested supplements. Or worse, you end up buying 9 products that each cost $30 each in order to get all the ingredients you are looking for, and you are paying for 20 ingredients that you didn’t want! That is, until Ergonine.

ERGONINE brings you the first ever NINE-IN-ONE foundational supplement product, a true daily ergogenic aid. No BS & trusted, effective, and all in a single product. A single scoop of Ergonine provides full servings of everything you need. Simply put, Ergonine is the foundation of every supplement stack you ever decide to use.



It looks like there’s a new contender in the strength and size department: Betaine Anhydrous. This exciting compound only recently came to researchers’ attention as they found it increases strength and muscle mass in a manner very similar to creatine when combined with exercise: by actively providing energy to your muscle cells.


In addition to this, betaine shares other effects with creatine: it reduces lactate production, it increases power output and explosiveness, it improves endurance, and it delays fatigue in trained subjects [10-13]. Betaine even creates a positive hormone environment by lowering the catabolic hormone cortisol [14]. And as you guessed, we used the 2.5 grams, the exact amount studied extensively in humans for all of these effects.

HydroMax® – 
Supercharged Glycerol

Glycerol products are well known for their ability to induce all day pumps and fullness, making you look and feel great inside and outside the gym.

Its purpose in ERGONINE is simple…The mechanism by which glycerol works synergizes perfectly with creatine and betaine anhydrous. On top of that…who doesn’t want to feel like their muscles are full all day?! Unfortunately, the glycerol products that are currently out there use glycerol monostearate, which is roughly ¼ glycerol and ¾ gunky saturated fat that clogs your shaker.

HydroMAX is the new age of glycerol, introducing a much higher potency of glycerol that is closer to roughly ¾ glycerol by weight!

L-Carnitine-L-Tartrate – 
The Most Effective Form of Carnitine for Athletes

L-carnitine, like L-glutamine, is another staple supplement that has been used for decades by bodybuilders. Unfortunately, studies on regular L-carnitine have found it ineffective in improving fat loss, even when combined with exercise [21]. Something was missing… Like SynerGlut before it, we found a way to finally make L-carnitine useful…and better: the answer is L-Carnitine-L-Tartrate (LCLT). LCLT is an amazing recovery aid, and it aids recovery through multiple angles. First, it reduces muscle catabolism and destruction as evidenced by muscle markers of damage [23, 32]. Next, it reduces lactate production by increasing oxygen delivery to muscle, which should result in reduced soreness by preventing acidosis.[22]

SynerGlut – 
Unlocking the Synergy of Glutamine with Alanine

As many of you know, glutamine has long been touted as the ultimate recovery amino acid since it is the most plentiful amino acid in muscle tissue. And yet, countless studies have shown that glutamine has no effect on muscle recovery; it’s nothing more than a placebo when taken as plain old L-Glutamine! [15,16]

This result came as a major shock to myself and many others, so I asked the ever elusive question: why does glutamine not work? The answer lies in the fact that glutamine is the primary amino acid that feeds the cells of your gut, so your intestines consume all the glutamine before they ever reach your muscles.

After over a year of research, we’ve found a novel way to bypass this problem. By consuming L-glutamine with L-alanine, glutamine delivery to muscle tissue is massively increased, and the recovery pathways can finally have potential [17-19]. And it doesn’t matter whether or not the glutamine is bonded to alanine as a dipeptide; combining L-glutamine with L-alanine in a blend has shown to be equally effective in mammals[20]…and this is precisely what we do.

Choline Bitartrate

You may recognize choline as a stimulant-free ingredient that increases focus and alertness by converting to acetylcholine in the body. But its inclusion in ERGONINE isn’t to enhance mental strength.

Rather, brand new data shows that in humans, choline has the ability to induce fat loss while supporting health and exercise performance[25]. 
Like LCLT, choline plays a vital role in exercise performance even if fat loss isn’t your goal[26]. For instance, exercise depletes choline stores which results in diminished physical performance. Heavy exercise can also deplete critical neurotransmitters for mood and energy levels, which is why you may often feel drained at the end of a heavy workout. Choline doubles up as a performance enhancer by keeping mood and energy levels stable during longer workouts and athletic events [31].

This is definitely something you want to take every day.


The L-Carnitine-L-Tartrate + Choline Combo: Maximize Your Carnitine

So Choline Bitartrate is a great ingredient in and of itself...but at Athletix, we don’t just toss promising ingredients together. We Formulate

You see, choline displays special synergy with the LCLT we mentioned above. Choline significantly reduces the amount of excreted carnitine so you get way more bang for your buck with each carnitine serving, and the net result is reduced body fat and increased levels of the fat burning hormone leptin [27,28].

So LCLT burns fat, choline burns fat…and when combined, they show synergy…1+1=3 Methylation Domination – A novel approach to performance enhancement

Methylation is a vital process in the body and may enhance exercise performance [35]. In fact, just for your body to make two of the ingredients mentioned above (creatine and carnitine), a methyl group must be “donated” from one molecule (the “donor”) to another molecule (the “recipient”).

n the case of creatine and carnitine, supplementing with methyl donors may help boost your body’s production of the two compounds. What this means is that you’ll be supplementing with creatine and carnitine, but you’ll also be putting your body in a position to make more of them yourself.

Again, we don’t just throw ingredients together…we formulate.

And so it was no coincidence that we elected to use betaine anhydrous and choline bitartrate in the formula, because both ingredients are among the most potent natural methyl donors [35].


HICA – Leucine’s Big Brother

Continuing our trend of taking fan favorite ingredients and providing you with more effective alternative forms, we’ve taken leucine, the key branched chain amino acid (BCAA) for muscle growth, and simplified it to its most metabolically active metabolite: HICA.

HICA, also known as Leucic Acid or Alpha-Hydroxy-Isocaproic Acid has been shown in elite athletes to increase muscle mass, reduce fat mass, reduce soreness, and improve performance. All at a dose of 1.5 grams…the exact dose we use in ERGONINE [24].

Ferulic Acid

Athletix is bringing you a totally novel, human-proven compound: ferulic acid. Ferulic acid has been known, in the murine model, to jack up exercise capacity [29,30]. Just 30 mg Ferulic Acid a day in well-trained weightlifters is enough to significantly enhance muscle mass, increase strength, and improve recovery[31]. And it does this with a unique mechanism unlike any other compound in ERGONINE, allowing you to hit muscle growth and performance enhancement from all angles.

This is the novel cherry on top of the most complete and proven formula you’ve ever used.








1. Jäger, Ralf, Martin Purpura, Andrew Shao, Toshitada Inoue, and Richard B. Kreider. "Analysis of the Efficacy, Safety, and Regulatory Status of Novel Forms of Creatine." Amino Acids 40.5 (2011): 1369-383. Web.


2. Juhász, Imre, I. Györe, Zs Csende, L. Rácz, and J. Tihanyi. "Creatine Supplementation Improves the Anaerobic Performance of Elite Junior Fin Swimmers." Acta Physiologica Hungarica 96.3 (2009): 325-36. Web.


3. Candow, Darren G., Philip D. Chilibeck, Darren G. Burke, Kristie D. Mueller, and Jessica D. Lewis. "Effect of Different Frequencies of Creatine Supplementation on Muscle Size and Strength in Young Adults." Journal of Strength and Conditioning Research 25.7 (2011): 1831-838. Web.


4. Favero, Serena, Hamilton Roschel, Guilherme Artioli, Carlos Ugrinowitsch, Valmor Tricoli, André Costa, Renato Barroso, Ana Lua Negrelli, Maria Concepción Otaduy, Cláudia Costa Leite, Antonio Herbert Lancha-Junior, and Bruno Gualano. "Creatine but Not Betaine Supplementation Increases Muscle Phosphorylcreatine Content and Strength Performance." Amino Acids 42.6 (2012): 2299-305. Web.


5. Bazzucchi, Ilenia, Francesco Felici, and Massimo Sacchetti. "Effect of Short-Term Creatine Supplementation on Neuromuscular Function." Medicine & Science in Sports & Exercise 41.10 (2009): 1934-941. Web.


6. Rahimi, Rahman. "Creatine Supplementation Decreases Oxidative DNA Damage and Lipid Peroxidation Induced by a Single Bout of Resistance Exercise." Journal of Strength and Conditioning Research 25.12 (2011): 3448-455. Web.


7. Wright, Glenn A., Peter W. Grandjean, and David D. Pascoe. "The Effects Of Creatine Loading On Thermoregulation And Intermittent Sprint Exercise Performance In A Hot Humid Environment." Journal of Strength and Conditioning Research 21.3 (2007): 655-60. Web.


8. Graef, Jennifer L., Abbie E. Smith, Kristina L. Kendall, David H. Fukuda, Jordan R. Moon, Travis W. Beck, Joel T. Cramer, and Jeffrey R. Stout. "The Effects of Four Weeks of Creatine Supplementation and High-intensity Interval Training on Cardiorespiratory Fitness: A Randomized Controlled Trial." Journal of the International Society of Sports Nutrition 6.1 (2009): 18. Web.


9. Hoffman J, Ratamess N, Kang J, Mangine G, Faigenbaum A, and Stout J. “Effect of creatine and beta-alanine supplementation on performance and endocrine responses in strength/power athletes.” International Journal of Sport Nutrition & Exercise Metabolism 16.4 (2006): 430-36. Web.


10. Trepanowski, John F., Tyler M. Farney, Cameron G. Mccarthy, Brian K. Schilling, Stuart A. Craig, and Richard J. Bloomer. "The Effects of Chronic Betaine Supplementation on Exercise Performance, Skeletal Muscle Oxygen Saturation and Associated Biochemical Parameters in Resistance Trained Men." Journal of Strength and Conditioning Research 25.12 (2011): 3461-471. Web.


11. Lee, Elaine C., Carl M. Maresh, William J. Kraemer, Linda M. Yamamoto, Disa L. Hatfield, Brooke L. Bailey, Lawrence E. Armstrong, Jeff S. Volek, Brendon P. Mcdermott, and Stuart As Craig. "Ergogenic Effects of Betaine Supplementation on Strength and Power Performance." Journal of the International Society of Sports Nutrition 7.1 (2010): 27. Web.


12. Pryor, J. Luke, Stuart As Craig, and Thomas Swensen. "Effect of Betaine Supplementation on Cycling Sprint Performance." Journal of the International Society of Sports Nutrition 9.1 (2012): 12. Web.


13. Hoffman, Jay R., Nicholas A. Ratamess, Jie Kang, Adam M. Gonzalez, Noah A. Beller, and Stuart A S Craig. "Effect of 15 Days of Betaine Ingestion on Concentric and Eccentric Force Outputs During Isokinetic Exercise." Journal of Strength and Conditioning Research 25.8 (2011): 2235-241. Web.


14. Apicella, Jenna M., Elaine C. Lee, Brooke L. Bailey, Catherine Saenz, Jeffrey M. Anderson, Stuart A. S. Craig, William J. Kraemer, Jeff S. Volek, and Carl M. Maresh. "Betaine Supplementation Enhances Anabolic Endocrine and Akt Signaling in Response to Acute Bouts of Exercise." European Journal of Applied Physiology 113.3 (2013): 793-802. Web.


15. Candow, Darren, Philip Chilibeck, Darren Burke, Shawn Davison, and Truis Smith-Palmer. "Effect of Glutamine Supplementation Combined with Resistance Training in Young Adults." European Journal of Applied Physiology 86.2 (2001): 142-49. Web.


16. Phillips, George C. "Glutamine: The Nonessential Amino Acid for Performance Enhancement." Current Sports Medicine Reports 6.4 (2007): 265-68. Web.


17. Harris, Roger C., Jay R. Hoffman, Adrian Allsopp, and Naomi B.h. Routledge. "L-glutamine Absorption Is Enhanced after Ingestion of L-alanylglutamine Compared with the Free Amino Acid or Wheat Protein." Nutrition Research 32.4 (2012): 272-77. Web.


18. Hoffman, Jay R., David R. Williams, Nadia S. Emerson, Mattan W. Hoffman, Adam J. Wells, Daniele M. Mcveigh, William P. Mccormack, Gerald T. Mangine, Adam M. Gonzalez, and Maren S. Fragala. "L-alanyl-L-glutamine Ingestion Maintains Performance during a Competitive Basketball Game." Journal of the International Society of Sports Nutrition 9.1 (2012): 4. Web.


19. Hoffman, Jay R., Nicholas A. Ratamess, Jie Kang, Stephanie L. Rashti, Neil Kelly, Adam M. Gonzalez, Michael Stec, Steven Anderson, Brooke L. Bailey, Linda M. Yamamoto, Lindsay L. Hom, Brian R. Kupchak, Avery D. Faigenbaum, and Carl M. Maresh. "Examination of the Efficacy of Acute L-alanyl-L-glutamine Ingestion during Hydration Stress in Endurance Exercise." Journal of the International Society of Sports Nutrition 7.1 (2010): 8. Web.


20. Cruzat, Vinicius Fernandes, and Julio Tirapegui. "Effects of Oral Supplementation with Glutamine and Alanyl-glutamine on Glutamine, Glutamate, and Glutathione Status in Trained Rats and Subjected to Long-duration Exercise." Nutrition 25.4 (2009): 428-35. Web.


21. Villani, R. G., J. Gannon, M. Self, and P. A. Rich. "L-Carnitine Supplementation Combined with Aerobic Training Does Not Promote Weight Loss in Moderately Obese Women." Int J Sport Nutr Exerc Metab 10.2 (2000): 199-207. Web.


22. Spiering, Barry A., William J. Kraemer, Disa L. Hatfield, Jakob L. Vingren, Maren S. Fragala, Jen-Yu Ho, Gwendolyn A. Thomas, Keijo Häkkinen, and Jeff S. Volek. "Effects of L-Carnitine L-Tartrate Supplementation on Muscle Oxygenation Responses to Resistance Exercise." Journal of Strength and Conditioning Research 22.4 (2008): 1130-135. Web.


23. Volek JS, Kraemer WJ, Rubin MR, Gómez AL, Ratamess NA, and Gaynor P. “L-Carnitine L-Tartrate Supplementation Favorably Affects Markers of Recovery from Exercise Stress.” American Journal of Physiology, Endocrinology and Metabolism 282.2 (2002): E474-82. Web.


24. Mero, Antti A., Tuomo Ojala, Juha J. Hulmi, Risto Puurtinen, Tuomo Am Karila, and Timo Seppälä. "Effects of Alfa-hydroxy-isocaproic Acid on Body Composition, DOMS and Performance in Athletes." Journal of the International Society of Sports Nutrition 7.1 (2010): 1. Web.


25. Penry, J. T., and M. M. Manore. "Choline: An Important Micronutrient for Maximal Endurance-exercise Performance?" Int J Sport Nutr Exerc Metab 18.2 (2008): 191-203. Web.


26. Elsawy, Gehan, Osama Abdelrahman, and Amr Hamza. "Effect of Choline Supplementation on Rapid Weight Loss and Biochemical Variables Among Female Taekwondo and Judo Athletes." J Hum Kinet 40 (2014): 77-82. Web.


27. Hungo, Nobuko, and Dileep S. Sachan. "Carnitine and Choline Supplementation with Exercise Alter Carnitine Profiles, Biochemical Markers of Fat Metabolism and Serum Leptin Concentration in Healthy Women." The Journal of Nutrition 133.1 (2003): 84-89. Web.


28. Hongu, N., and D. S. Sachan. "Caffeine, Carnitine and Choline Supplementation of Rats Decreases Body Fat and Serum Leptin Concentration as Does Exercise." The Journal of Nutrition 130.2 (2000): 152-57. Web.


29. You, Yanghee, Kyungmi Kim, Ho-Geun Yoon, Kwang-Won Lee, Jeongmin Lee, Jiyeon Chun, Dong-Hoon Shin, Jeongjin Park, and Woojin Jun. "Chronic Effect of Ferulic Acid from Pseudosasa Japonica Leaves on Enhancing Exercise Activity in Mice."Phytotherapy Research 24.10 (2010): 1508-513. Web.


30. You, Yanghee, Jeongjin Park, Ho-Geun Yoon, Yoo-Hyun Lee, Kwontack Hwang, Jeongmin Lee, Kyungmi Kim, Kwang-Won Lee, Sangin Shim, and Woojin Jun. "Stimulatory Effects of Ferulic Acid on Endurance Exercise Capacity in Mice." Bioscience, Biotechnology, and Biochemistry 73.6 (2009): 1392-397. Web.


31. Wolinsky, Ira. Nutrition in Exercise and Sport. Boca Raton: CRC, 1998. Print.


32. Ho, Jen-Yu, William J. Kraemer, Jeff S. Volek, Maren S. Fragala, Gwendolyn A. Thomas, Courtenay Dunn-Lewis, Michael Coday, Keijo Häkkinen, and Carl M. Maresh. "L-Carnitine L-tartrate Supplementation Favorably Affects Biochemical Markers of Recovery from Physical Exertion in Middle-aged Men and Women." Metabolism 59.8 (2010): 1190-199. Web.


While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Nutriverse assumes no liability for inaccuracies or misstatements about products.

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